There is serious traffic disruption in and around the Dry Arch Roundabout as a result.
One eye-witness told us that it looks like two of the vehicles are seriously damaged.
It is unclear as to how the accident happened or how bad the injuries are.
Both the Gardai and ambulances are on scene to help the victims of the smash.
The eye-witness said: “It looks pretty bad but it’s hard to say if anyone is seriously hurt.
“A couple of the cars I saw look pretty bad.
“The Gardai and at least two ambulances were there. Hopefully everyone involved will be okay,” said the man.