The National Public Health Emergency Team (Nphet) has given the green light for lifting almost all Covid-19 restrictions.
The majority of measures may be lifted in the coming days.
The changes will see pubs and restaurants returning to normal service, marking a major boost for the industry.
Late night entertainment and nightclubs could also reopen.
Other limits on household visits and capacity on sporting events or weddings will be eased.
The timeline of the reopening plan has not been set yet, but hospitality chiefs say they are “ready and waiting to open our doors this weekend”.
The recommendations were made by NPHET at a meeting yesterday, after which they declared that the Omicron peak is now over and it is safe to move forward.
A Cabinet will take place at 3pm today to discuss NPHET’s advice. A televised address is expected to follow from An Taoiseach Micheál Martin this evening.