The Doochary to Lettermacaward (L1783-3) will be blocked for the next two days.
The closure is to allow for essential roadworks.
Donegal County Council says the road will be blocked tomorrow Wednesday 27th & Thursday 28th March from 8.00am to 5.00pm on both days.
The exact location of the road blockage is at Derryhenny.
It is advised to use alternative routes during these times.
Donegal County Council has apologised for any inconvenience which this may cause.